Sickle Cell Complications

You're probably hydrating wrong during a sickle cell crisis

Learn the most effective ways to hydrate during sickle cell crises
Dr Lewis Thomas
August 23, 2026

You feel that all too familiar first twinge of pain.

As much as you hope its nothing sickle related you know it's time to take crisis prevention measures.

The first thing to do?

Get as hydrated as possible, as fast as possible.

This is the moment you may consider what actually is the best way to do that?

Perhaps those glowing blue sports electrolyte hydration drinks.

They're scientifically designed to hydrate athletes quick right?

Perhaps those Oral Rehydration Sachets (ORS) doctors prescribe to sick dehydrated kids in hospital.

If they're good enough to prescribe why not just keep a stock of them for whenever rapid rehydration is needed?

It feels like the right call, it sounds medical, it's what people recommend.

But here's the thing: it might not be what your body actually needs right now.

What these fluids are actually designed for

Dehydration isn't just caused by not taking enough fluid into your body.

It's also caused by losing too much fluid out of your body.

Vomiting, diarrhoea and heavy sweating.

These are all situations where salts and minerals are mass exiting the body.

Electrolyte drinks and oral rehydration solutions are built to replace what's lost.

In those situations, they work brilliantly to rehydrate you AND solve the problem of lost salts and minerals.

But during a typical sickle cell pain crisis, without those symptoms? Your electrolyte levels are probably fine. What you're short on is water. And plain water, in that situation, is absorbed more efficiently and gets to work faster.

The sports drink isn't wrong. It's just solving a problem you don't have.

So what should you actually do?

Keep it simple. If your crisis involves vomiting or significant sweating, an electrolyte drink or Oral Rehydration Sachet makes sense — that's the right tool for that situation.

But if it's a pain episode without those symptoms, plain water is your best option.

Drink steadily and consistently rather than trying to down large amounts quickly. Room temperature or warm water tends to be easier to tolerate than cold.

And if you're struggling to keep any fluids down - that's the point to seek medical support rather than push through at home.

The best hydration strategy isn't always the most fancy one. Sometimes the right answer really is just water.

Stay Healthy,


Lewis

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